Abstract
Perfusion of rat groin flaps after 10 and 11 hours of complete ischemia with superoxide dismutase, an oxygen free-radical scavenger, significantly improved the survival of these flaps. This finding provides further evidence for the important role that oxygen-derived free radicals play in ischemic injury. The study also demonstrates that while restoration of blood supply alone is not enough to ensure tissue survival after prolonged ischemia, chemical agents can be utilized to achieve viable flaps beyond what was believed to be “a point of no return.
| Original language | English |
|---|---|
| Pages (from-to) | 638-642 |
| Number of pages | 5 |
| Journal | Plastic and Reconstructive Surgery |
| Volume | 77 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1 Jan 1986 |
| Externally published | Yes |
ASJC Scopus subject areas
- Surgery