Incidental Detection of Malignant Melanoma Brain Recurrence on 68Ga-Prostate-Specific Membrane Antigen PET/CT

Nir Hod, Sophie Lantsberg, Elya Benkovich, Dina Ezroh Kazap, Mark Preiskel, Daniel Levin

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A 76-year-old man with a prior medical history of resected malignant melanoma of the skull underwent 68Ga-prostate-specific membrane antigen (PSMA) PET/CT due to rising tumor markers of a known prostate carcinoma. Unexpected high 68Ga-PSMA brain uptake was encountered around the surgical cavity in the skull with initially no specific structural changes on anatomical imaging. Successive CT and MRI eventually revealed local melanoma brain recurrence at this site. This interesting case demonstrates the diagnostic potential of 68Ga-PSMA PET/CT imaging for detection of malignant melanoma brain recurrence.

Original languageEnglish
Pages (from-to)896-899
Number of pages4
JournalClinical Nuclear Medicine
Volume45
Issue number11
DOIs
StatePublished - Nov 2020

Keywords

  • Ga-PSMA
  • brain tumor
  • incidentaloma
  • malignant melanoma
  • MRI
  • PET/CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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