Incidental Detection of Radiotracer Uptake in Intracranial Dermoid Cyst on 18F-Prostate-Specific Membrane Antigen PET/CT during Staging for Prostate Carcinoma

Nir Hod, Daniel Levin, Rosa Novoa, Sophie Lantsberg

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A 68-year-old man underwent 18F-prostate-specific membrane antigen (PSMA) PET/CT for staging of a newly diagnosed prostate adenocarcinoma. Unexpectedly, PET/CT revealed high focal 18F-PSMA brain uptake, which initially was suspected for a brain metastasis. Corresponding CT and MRI scans revealed characteristic imaging features of an intracranial dermoid cyst at this site. This is an exceptional location for a dermoid cyst, which had been followed up conservatively with no substantial changes. This case shows that dermoid cyst should be added to the reported list of benign neoplasms that shows "false-positive"PSMA uptake during evaluation of patients with prostate carcinoma, representing a potential interpretative pitfall.

Original languageEnglish
Pages (from-to)E273-E275
JournalClinical Nuclear Medicine
Volume46
Issue number5
DOIs
StatePublished - May 2021

Keywords

  • F-PSMA
  • "false-positive"
  • brain neoplasm
  • dermoid cyst
  • intracranial tumor
  • PET/CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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