Incidental Detection of Radiotracer Uptake in Spindle Cell Lipoma on 18F-PSMA PET/CT

Nir Hod; Yehonatan Sherf; Sophie Lantsberg

doi:10.1097/RLU.0000000000004291

Incidental Detection of Radiotracer Uptake in Spindle Cell Lipoma on ¹⁸F-PSMA PET/CT

Nir Hod, Yehonatan Sherf, Sophie Lantsberg

Research output: Contribution to journal › Article › peer-review

Abstract

An 84-year-old man underwent 18F-prostate-specific membrane antigen (PSMA) PET/CT for staging of a newly diagnosed prostate adenocarcinoma. PET/CT revealed high 18F-PSMA uptake in a thigh mass, which was initially suspected for a metastasis. Histopathology revealed a rare entity of spindle cell lipoma, which should be added to the reported list of neoplasms that can show "false-positive"PSMA uptake during evaluation of patients with prostate carcinoma representing a potential interpretative pitfall.

Original language	English
Pages (from-to)	E663-E665
Journal	Clinical Nuclear Medicine
Volume	47
Issue number	10
DOIs	https://doi.org/10.1097/RLU.0000000000004291
State	Published - Oct 2022

Keywords

"false-positive"
F-PSMA
PET/CT
soft tissue tumor
spindle cell lipoma

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1097/RLU.0000000000004291

Cite this

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title = "Incidental Detection of Radiotracer Uptake in Spindle Cell Lipoma on 18F-PSMA PET/CT",

abstract = "An 84-year-old man underwent 18F-prostate-specific membrane antigen (PSMA) PET/CT for staging of a newly diagnosed prostate adenocarcinoma. PET/CT revealed high 18F-PSMA uptake in a thigh mass, which was initially suspected for a metastasis. Histopathology revealed a rare entity of spindle cell lipoma, which should be added to the reported list of neoplasms that can show {"}false-positive{"}PSMA uptake during evaluation of patients with prostate carcinoma representing a potential interpretative pitfall.",

keywords = "{"}false-positive{"}, F-PSMA, PET/CT, soft tissue tumor, spindle cell lipoma",

author = "Nir Hod and Yehonatan Sherf and Sophie Lantsberg",

note = "Publisher Copyright: {\textcopyright} 2022 Wolters Kluwer Health, Inc.",

year = "2022",

month = oct,

doi = "10.1097/RLU.0000000000004291",

language = "English",

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pages = "E663--E665",

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AU - Hod, Nir

AU - Sherf, Yehonatan

AU - Lantsberg, Sophie

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Y1 - 2022/10

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AB - An 84-year-old man underwent 18F-prostate-specific membrane antigen (PSMA) PET/CT for staging of a newly diagnosed prostate adenocarcinoma. PET/CT revealed high 18F-PSMA uptake in a thigh mass, which was initially suspected for a metastasis. Histopathology revealed a rare entity of spindle cell lipoma, which should be added to the reported list of neoplasms that can show "false-positive"PSMA uptake during evaluation of patients with prostate carcinoma representing a potential interpretative pitfall.

KW - "false-positive"

KW - F-PSMA

KW - PET/CT

KW - soft tissue tumor

KW - spindle cell lipoma

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