Increase in Haemophilus influenzae Detection in 13-Valent Pneumococcal Conjugate Vaccine Immunized Children With Acute Otitis Media

Ayala Klein; Sharon Ovnat Tamir; Nadav Sorek; Galia Hanun; Yonatan Yeshayahu; Tal Marom

doi:10.1097/INF.0000000000003561

Increase in Haemophilus influenzae Detection in 13-Valent Pneumococcal Conjugate Vaccine Immunized Children With Acute Otitis Media

Ayala Klein, Sharon Ovnat Tamir, Nadav Sorek, Galia Hanun, Yonatan Yeshayahu, Tal Marom

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

NTHi was the predominant pathogen in ear cultures from severe acute otitis media (AOM) episodes in PCV-13 vaccinated children, more commonly in girls. NTHi-AOM episodes were associated with more myringotomies due to a higher treatment failure incidence. The low rate of β-lactamase NTHi isolates in middle ear fluid cultures from PCV-13 vaccinated children presenting with AOM strengthens to still use amoxicillin as the first-line antibiotics.

Original language	English
Pages (from-to)	678-680
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	41
Issue number	8
DOIs	https://doi.org/10.1097/INF.0000000000003561
State	Published - 1 Aug 2022

Keywords

amoxicillin
prevalence
treatment failure

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/INF.0000000000003561

Cite this

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title = "Increase in Haemophilus influenzae Detection in 13-Valent Pneumococcal Conjugate Vaccine Immunized Children With Acute Otitis Media",

abstract = "NTHi was the predominant pathogen in ear cultures from severe acute otitis media (AOM) episodes in PCV-13 vaccinated children, more commonly in girls. NTHi-AOM episodes were associated with more myringotomies due to a higher treatment failure incidence. The low rate of β-lactamase NTHi isolates in middle ear fluid cultures from PCV-13 vaccinated children presenting with AOM strengthens to still use amoxicillin as the first-line antibiotics.",

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T1 - Increase in Haemophilus influenzae Detection in 13-Valent Pneumococcal Conjugate Vaccine Immunized Children With Acute Otitis Media

AU - Klein, Ayala

AU - Tamir, Sharon Ovnat

AU - Sorek, Nadav

AU - Hanun, Galia

AU - Yeshayahu, Yonatan

AU - Marom, Tal

PY - 2022/8/1

Y1 - 2022/8/1

N2 - NTHi was the predominant pathogen in ear cultures from severe acute otitis media (AOM) episodes in PCV-13 vaccinated children, more commonly in girls. NTHi-AOM episodes were associated with more myringotomies due to a higher treatment failure incidence. The low rate of β-lactamase NTHi isolates in middle ear fluid cultures from PCV-13 vaccinated children presenting with AOM strengthens to still use amoxicillin as the first-line antibiotics.

AB - NTHi was the predominant pathogen in ear cultures from severe acute otitis media (AOM) episodes in PCV-13 vaccinated children, more commonly in girls. NTHi-AOM episodes were associated with more myringotomies due to a higher treatment failure incidence. The low rate of β-lactamase NTHi isolates in middle ear fluid cultures from PCV-13 vaccinated children presenting with AOM strengthens to still use amoxicillin as the first-line antibiotics.

KW - amoxicillin

KW - prevalence

KW - treatment failure

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JF - Pediatric Infectious Disease Journal

IS - 8

ER -

Increase in Haemophilus influenzae Detection in 13-Valent Pneumococcal Conjugate Vaccine Immunized Children With Acute Otitis Media

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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