Increased coagulation factor levels leading to allograft renal vein thrombosis

M. J. Hausmann, M. Vorobiov, M. Zlotnik, B. Rogachev, A. Tomer

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A patient with end-stage kidney disease is described, who lost his renal allograft in the early post-transplant period due to allograft renal vein thrombosis. Prior to transplantation, he had been treated by hemodialysis and lost several vascular accesses because of thrombosis. A search for potential thrombophilic factors disclosed a unique combination of increased clotting factor levels, i.e. FVIII, FIX, FXI and homocysteine. More common hereditary and acquired hypercoagulability factors have been excluded in this patient. While clotting factor deficiencies are well known causes of hemophilia, their levels should also be measured in the workup of transplant candidates with a history of multiple vascular access thrombosis.

Original languageEnglish
Pages (from-to)222-224
Number of pages3
JournalClinical Nephrology
Volume61
Issue number3
DOIs
StatePublished - 1 Jan 2004

Keywords

  • Allograft thrombosis
  • Coagulation factor
  • Factor VIII
  • Renal vein thrombosis
  • Thrombophilia

ASJC Scopus subject areas

  • Nephrology

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