TY - JOUR
T1 - Increased decidual prostaglandin E concentration in human abortion
AU - JASCHEVATZKY, OSCAR E.
AU - SHALIT, AMOS
AU - GRUNSTEIN, STEPHAN
AU - KAPLANSKI, JACOB
AU - DANON, ABRAHAM
PY - 1983/1/1
Y1 - 1983/1/1
N2 - Summary. Prostaglandin E (PGE) concentration was measured in decidual tissue after spontaneous and missed abortion and compared with that obtained from induced abortion. Tissues were obtained by curettage from groups of 10 patients each and PGE was estimated by radioimmunoassay. After spontaneous and missed abortions decidual tissue contained significantly higher mean concentrations of PGE, (486.3 and 66.7 ng/g wet tissue respectively) than after induced abortion (18.6 ng PGE/g wet tissue). It is suggested that an increased rate of PGE biosynthesis or reduced breakdown, or both, may play a role in the mechanism of human abortion.
AB - Summary. Prostaglandin E (PGE) concentration was measured in decidual tissue after spontaneous and missed abortion and compared with that obtained from induced abortion. Tissues were obtained by curettage from groups of 10 patients each and PGE was estimated by radioimmunoassay. After spontaneous and missed abortions decidual tissue contained significantly higher mean concentrations of PGE, (486.3 and 66.7 ng/g wet tissue respectively) than after induced abortion (18.6 ng PGE/g wet tissue). It is suggested that an increased rate of PGE biosynthesis or reduced breakdown, or both, may play a role in the mechanism of human abortion.
UR - http://www.scopus.com/inward/record.url?scp=0020517025&partnerID=8YFLogxK
U2 - 10.1111/j.1471-0528.1983.tb06770.x
DO - 10.1111/j.1471-0528.1983.tb06770.x
M3 - Article
C2 - 6626492
AN - SCOPUS:0020517025
SN - 1470-0328
VL - 90
SP - 958
EP - 960
JO - BJOG: An International Journal of Obstetrics and Gynaecology
JF - BJOG: An International Journal of Obstetrics and Gynaecology
IS - 10
ER -