Indirect protection of children from SARS-CoV-2 infection through parental vaccination

Samah Hayek, Galit Shaham, Yatir Ben-Shlomo, Eldad Kepten, Noa Dagan, Daniel Nevo, Marc Lipsitch, Ben Y Reis, Ran D Balicer, Noam Barda

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Children unvaccinated against SARS-CoV-2 may still benefit through protection from vaccinated contacts. We estimated the protection provided to children through parental vaccination with the BNT162b2 vaccine. We studied households without prior infection, consisting of two parents and unvaccinated children, estimating the effect of parental vaccination on the risk of infection for unvaccinated children. We studied two periods separately- an early period (January 17, 2021 - March 28, 2021, Alpha variant, two doses vs. no vaccination) and a late period (July 11, 2021 - September 30, 2021, Delta variant, booster dose vs. two-vaccine doses). We found that having a single vaccinated parent was associated with a 26.0% and 20.8% decreased risk, and having two vaccinated parents was associated with a 71.7% and 58.1% decreased risk, in the early and late periods, respectively. To conclude, parental vaccination confers substantial protection for unvaccinated children in the household.

Original languageEnglish
Pages (from-to)eabm3087
Number of pages5
Issue number6585
StateE-pub ahead of print - 27 Jan 2022


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