Indium tin oxide-coated optical fiber tips for affinity electropolymerization

R. S. Marks, A. Novoa, T. Konry, R. Krais, S. Cosnier

    Research output: Contribution to journalArticlepeer-review

    33 Scopus citations

    Abstract

    We demonstrate herein that it is possible to create surface-conductive fiber optics, upon which may be electropolymerized a biotinylated polypyrrole thin film, which may then be used to affinity coat the fiber with recognition probes. This fiberoptic electroconductive surface modification is done by the deposition of a thin layer of indium tin oxide. Thereafter, biotin-pyrrole monomers are electropolymerized onto the conductive metal oxide surface. We were able to demonstrate the presence of an electropolymerized polypyrrole-biotin film by allowing horseradish-peroxidase-labeled avidin to link to it and thereafter exposing it to luminol in order to obtain a chemiluminescence radiation.

    Original languageEnglish
    Pages (from-to)189-194
    Number of pages6
    JournalMaterials Science and Engineering C
    Volume21
    Issue number1-2
    DOIs
    StatePublished - 1 Sep 2002

    Keywords

    • Avidin-biotin
    • Electrochemistry
    • Indium tin oxide
    • Optical fiber
    • Polypyrrole

    ASJC Scopus subject areas

    • Materials Science (all)
    • Condensed Matter Physics
    • Mechanics of Materials
    • Mechanical Engineering

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