Individual differences and evidence-based psychopharmacology

R. H. Belmaker; Yuly Bersudsky; Galila Agam

doi:10.1186/1741-7015-10-110

Individual differences and evidence-based psychopharmacology

R. H. Belmaker, Yuly Bersudsky, Galila Agam

Research output: Contribution to journal › Comment/debate

10 Scopus citations

Abstract

Individual differences in response to pharmacologic treatment limits the usefulness of mean data obtained from randomized controlled trials. These individual differences exist even in genetically uniform inbred mouse strains. While stratification can be of value in large studies, the individual patient history is the most effective currently available guide for personalized medicine in psychopharmacology.

Original language	English
Article number	110
Journal	BMC Medicine
Volume	10
DOIs	https://doi.org/10.1186/1741-7015-10-110
State	Published - 27 Sep 2012

Keywords

Clinical Trials
Individual Differences
Measurement Error
Replicability
Variability
Variance

ASJC Scopus subject areas

Medicine (all)

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10.1186/1741-7015-10-110

Cite this

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title = "Individual differences and evidence-based psychopharmacology",

abstract = "Individual differences in response to pharmacologic treatment limits the usefulness of mean data obtained from randomized controlled trials. These individual differences exist even in genetically uniform inbred mouse strains. While stratification can be of value in large studies, the individual patient history is the most effective currently available guide for personalized medicine in psychopharmacology.",

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author = "Belmaker, {R. H.} and Yuly Bersudsky and Galila Agam",

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T1 - Individual differences and evidence-based psychopharmacology

AU - Belmaker, R. H.

AU - Bersudsky, Yuly

AU - Agam, Galila

PY - 2012/9/27

Y1 - 2012/9/27

N2 - Individual differences in response to pharmacologic treatment limits the usefulness of mean data obtained from randomized controlled trials. These individual differences exist even in genetically uniform inbred mouse strains. While stratification can be of value in large studies, the individual patient history is the most effective currently available guide for personalized medicine in psychopharmacology.

AB - Individual differences in response to pharmacologic treatment limits the usefulness of mean data obtained from randomized controlled trials. These individual differences exist even in genetically uniform inbred mouse strains. While stratification can be of value in large studies, the individual patient history is the most effective currently available guide for personalized medicine in psychopharmacology.

KW - Clinical Trials

KW - Individual Differences

KW - Measurement Error

KW - Replicability

KW - Variability

KW - Variance

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U2 - 10.1186/1741-7015-10-110

DO - 10.1186/1741-7015-10-110

M3 - Comment/debate

C2 - 23016518

AN - SCOPUS:84866661115

SN - 1741-7015

VL - 10

JO - BMC Medicine

JF - BMC Medicine

M1 - 110

ER -

Individual differences and evidence-based psychopharmacology

Abstract

Keywords

ASJC Scopus subject areas

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