Individual differences and evidence-based psychopharmacology

R. H. Belmaker, Yuly Bersudsky, Galila Agam

    Research output: Contribution to journalComment/debate

    7 Scopus citations

    Abstract

    Individual differences in response to pharmacologic treatment limits the usefulness of mean data obtained from randomized controlled trials. These individual differences exist even in genetically uniform inbred mouse strains. While stratification can be of value in large studies, the individual patient history is the most effective currently available guide for personalized medicine in psychopharmacology.

    Original languageEnglish
    Article number110
    JournalBMC Medicine
    Volume10
    DOIs
    StatePublished - 27 Sep 2012

    Keywords

    • Clinical Trials
    • Individual Differences
    • Measurement Error
    • Replicability
    • Variability
    • Variance

    ASJC Scopus subject areas

    • Medicine (all)

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