Induction of spermatogenesis in hypogonadotrophic hypogonadism

I. M. Spitz, Z. Schumert, J. Steiner, E. Rosen, S. Segal, A. Slonim, D. Rabinowitz

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


A young male who presented with isolated bihormonal gonadotrophin deficiency is described. Basal levels of LH and FSH were low and there was no response to clomiphene citrate or LHRH. The remaining anterior pituitary function was intact. The administration of a combination of human menopausal gonadotrophin and human chorionic gonadotrophin caused testicular maturation with spermatogenesis and full androgenization. The patient was able to father a child.

Original languageEnglish
Pages (from-to)694-697
Number of pages4
JournalPostgraduate Medical Journal
Issue number636
StatePublished - 1 Jan 1978
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (all)


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