Infectious diseases are analogous with cancer. Hypothesis and implications

  • Daniel Benharroch
  • , Lidia Osyntsov

    Research output: Contribution to journalArticlepeer-review

    29 Scopus citations

    Abstract

    We propose to disclose first degree analogous features between cancer and infectious dis-eases and to find out whether these similarities are superficial and negligible, due to the use of the same bodily pathways by the two categories of disease or if they represent significantly parallel characteristics. We have found several primary analogous features, predominantly regarding pathways of spread, but to some extent also concerning the interaction with the immune system. Some of the implications to our hypothesis are probably available in the recent literature, at the experimental or clinical levels. For example endostatin, an angiogenic inhibitor has been used to prevent promotion of metastasis in cancer and to reduce granu-lomas formation in schistosomiasis. An ECFR antagonist employed to restrain bronchial vessels proliferation in pseudomonas infection, has also been used for the treatment of lung cancer.

    Original languageEnglish
    Pages (from-to)117-121
    Number of pages5
    JournalJournal of Cancer
    Volume3
    Issue number1
    DOIs
    StatePublished - 23 Apr 2012

    Keywords

    • Analogy
    • Cancer
    • Immunity
    • Infectious disease
    • Spread

    ASJC Scopus subject areas

    • Oncology

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