Inflammatory bowel disease in migrant and native jewish populations of southern Israel

Ulcerative colitis and Crohn's disease were studied in three Jewish populations in the Beer Sheva district of southern Israel. Age-adjusted prevalence rates on 31 December 1987 were for ulcerative colitis, 89/10⁵, and for Crohn's disease, 30/1O⁵. Both diseases were commoner in females and in European-American-born Jews. Age-adjusted incidence rates have increased and in 1979-1987 were for ulcerative colitis, 5.4/10⁵/year, and for Crohn's disease, 2.1/10⁵/year. Females developed ulcerative colitis at a younger age and Crohn's disease at a later age than males. Israel-born patients developed both diseases at a young age. The clinical features of ulcerative colitis were similar in the various populations. Epidemiologic data in Jews may aid in the understanding of the pathogenesis of inflammatory bowel diseases.