Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: implications for clinical disease.

Helga E. de Vries, Gijs Kooij, Dan Frenkel, Spiros Georgopoulos, Alon Monsonego, Damir Janigro

Research output: Contribution to journalReview articlepeer-review

90 Scopus citations

Abstract

Proper function of the neurovasculature is required for optimal brain function and preventing neuroinflammation and neurodegeneration. Within this review, we discuss alterations of the function of the blood-brain barrier in neurologic disorders such as multiple sclerosis, epilepsy, and Alzheimer's disease and address potential underlying mechanisms. Wiley Periodicals, Inc.

Original languageEnglish
Pages (from-to)45-52
Number of pages8
JournalEpilepsia
Volume53 Suppl 6
DOIs
StatePublished - 1 Jan 2012

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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