Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: implications for clinical disease.

Helga E. de Vries; Gijs Kooij; Dan Frenkel; Spiros Georgopoulos; Alon Monsonego; Damir Janigro

doi:10.1111/j.1528-1167.2012.03702.x

Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: implications for clinical disease.

Helga E. de Vries
, Gijs Kooij
, Dan Frenkel
, Spiros Georgopoulos
, Alon Monsonego
, Damir Janigro

The Shraga Segal Department of Microbiology, Immunology and Genetics

Research output: Contribution to journal › Review article › peer-review

98 Scopus citations

Abstract

Proper function of the neurovasculature is required for optimal brain function and preventing neuroinflammation and neurodegeneration. Within this review, we discuss alterations of the function of the blood-brain barrier in neurologic disorders such as multiple sclerosis, epilepsy, and Alzheimer's disease and address potential underlying mechanisms. Wiley Periodicals, Inc.

Original language	English
Pages (from-to)	45-52
Number of pages	8
Journal	Epilepsia
Volume	53 Suppl 6
DOIs	https://doi.org/10.1111/j.1528-1167.2012.03702.x
State	Published - 1 Jan 2012

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1111/j.1528-1167.2012.03702.x

Cite this

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abstract = "Proper function of the neurovasculature is required for optimal brain function and preventing neuroinflammation and neurodegeneration. Within this review, we discuss alterations of the function of the blood-brain barrier in neurologic disorders such as multiple sclerosis, epilepsy, and Alzheimer's disease and address potential underlying mechanisms. Wiley Periodicals, Inc.",

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T2 - implications for clinical disease.

AU - de Vries, Helga E.

AU - Kooij, Gijs

AU - Frenkel, Dan

AU - Georgopoulos, Spiros

AU - Monsonego, Alon

AU - Janigro, Damir

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Proper function of the neurovasculature is required for optimal brain function and preventing neuroinflammation and neurodegeneration. Within this review, we discuss alterations of the function of the blood-brain barrier in neurologic disorders such as multiple sclerosis, epilepsy, and Alzheimer's disease and address potential underlying mechanisms. Wiley Periodicals, Inc.

AB - Proper function of the neurovasculature is required for optimal brain function and preventing neuroinflammation and neurodegeneration. Within this review, we discuss alterations of the function of the blood-brain barrier in neurologic disorders such as multiple sclerosis, epilepsy, and Alzheimer's disease and address potential underlying mechanisms. Wiley Periodicals, Inc.

UR - https://www.scopus.com/pages/publications/84872193915

U2 - 10.1111/j.1528-1167.2012.03702.x

DO - 10.1111/j.1528-1167.2012.03702.x

M3 - Review article

C2 - 23134495

AN - SCOPUS:84872193915

SN - 0013-9580

VL - 53 Suppl 6

SP - 45

EP - 52

JO - Epilepsia

JF - Epilepsia

ER -

Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: implications for clinical disease.

Abstract

ASJC Scopus subject areas

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