Abstract
We report a spectroscopic technique that combines the Fourier-Transform Infrared Spectroscopy with the Surface Plasmon Resonance. This tool enables sensitive infrared spectroscopy of liquid and solid objects in the attenuated total reflectance mode. The FTIR-SPR technique is similar to FTIR-ATR technique but has higher sensitivity due to resonance amplification of the surface electric field. The label-free FTIR-SPR technique is especially advantageous for living cell studies since it combines spectroscopic information inherent to FTIR with structural information provided by the Surface Plasmon Resonance. We discuss the FTIR-SPR technique for label-free studies of cell sedimentation and spreading on substrate and for surface plasmon spectroscopy.
| Original language | English |
|---|---|
| Title of host publication | Plasmons |
| Subtitle of host publication | Theory and Applications |
| Publisher | Nova Science Publishers, Inc. |
| Pages | 327-343 |
| Number of pages | 17 |
| ISBN (Electronic) | 9781617614217 |
| ISBN (Print) | 9781617613067 |
| State | Published - 1 Feb 2011 |
| Externally published | Yes |
Keywords
- Biosensor
- Cell culture
- FTIR
- Infrared
- Surface plasmon
ASJC Scopus subject areas
- General Physics and Astronomy