Inhibition of Acinetobacter nosocomialis twitching motility by quinolones produced by Pseudomonas aeruginosa

Nadeem Alatawneh; Manikandan Thangaraj; Michael M. Meijler

doi:10.1039/d4cc04270k

Inhibition of Acinetobacter nosocomialis twitching motility by quinolones produced by Pseudomonas aeruginosa

Nadeem Alatawneh
, Manikandan Thangaraj
, Michael M. Meijler

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Twitching motility in A. nosocomialis is a key virulence factor linked to antibiotic resistance and pathogenicity. This study revealed that the Pseudomonas quinolone signal (PQS) and hydroxy-containing quinolones significantly inhibit motility without affecting bacterial growth, highlighting their potential as targets for controlling bacterial virulence.

Original language	English
Pages (from-to)	12533-12536
Number of pages	4
Journal	Chemical Communications
Volume	60
Issue number	86
DOIs	https://doi.org/10.1039/d4cc04270k
State	Published - 8 Oct 2024

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/d4cc04270k

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title = "Inhibition of Acinetobacter nosocomialis twitching motility by quinolones produced by Pseudomonas aeruginosa",

abstract = "Twitching motility in A. nosocomialis is a key virulence factor linked to antibiotic resistance and pathogenicity. This study revealed that the Pseudomonas quinolone signal (PQS) and hydroxy-containing quinolones significantly inhibit motility without affecting bacterial growth, highlighting their potential as targets for controlling bacterial virulence.",

author = "Nadeem Alatawneh and Manikandan Thangaraj and Meijler, \{Michael M.\}",

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year = "2024",

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doi = "10.1039/d4cc04270k",

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AU - Alatawneh, Nadeem

AU - Thangaraj, Manikandan

AU - Meijler, Michael M.

PY - 2024/10/8

Y1 - 2024/10/8

N2 - Twitching motility in A. nosocomialis is a key virulence factor linked to antibiotic resistance and pathogenicity. This study revealed that the Pseudomonas quinolone signal (PQS) and hydroxy-containing quinolones significantly inhibit motility without affecting bacterial growth, highlighting their potential as targets for controlling bacterial virulence.

AB - Twitching motility in A. nosocomialis is a key virulence factor linked to antibiotic resistance and pathogenicity. This study revealed that the Pseudomonas quinolone signal (PQS) and hydroxy-containing quinolones significantly inhibit motility without affecting bacterial growth, highlighting their potential as targets for controlling bacterial virulence.

UR - https://www.scopus.com/pages/publications/85205877365

U2 - 10.1039/d4cc04270k

DO - 10.1039/d4cc04270k

M3 - Article

C2 - 39380548

AN - SCOPUS:85205877365

SN - 1359-7345

VL - 60

SP - 12533

EP - 12536

JO - Chemical Communications

JF - Chemical Communications

IS - 86

ER -

Inhibition of Acinetobacter nosocomialis twitching motility by quinolones produced by Pseudomonas aeruginosa

Abstract

ASJC Scopus subject areas

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