Inhibition of human platelet mitochondrial protein synthesis by chloramphenicol

G. Agam; M. Djaldetti

Inhibition of human platelet mitochondrial protein synthesis by chloramphenicol

G. Agam
, M. Djaldetti

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Human platelet mitochrondial protein synthesis, assayed by 'in vitro' ³H leucine incorporation into the protein moiety of isolated mitochondria, was shown to be inhibited by a therapeutic concentration of chloramphenical (CAP). This finding is in accordance with the ultrastructural damage caused to these organelles by the antibiotic, and with the inhibition of mitochondrial protein synthesis found in other kinds of mammalian cells.

Original language	English
Pages (from-to)	66-69
Number of pages	4
Journal	Biomedicine Express
Volume	27
Issue number	2
State	Published - 1 Jan 1977
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

General Medicine

Cite this

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title = "Inhibition of human platelet mitochondrial protein synthesis by chloramphenicol",

abstract = "Human platelet mitochrondial protein synthesis, assayed by 'in vitro' 3H leucine incorporation into the protein moiety of isolated mitochondria, was shown to be inhibited by a therapeutic concentration of chloramphenical (CAP). This finding is in accordance with the ultrastructural damage caused to these organelles by the antibiotic, and with the inhibition of mitochondrial protein synthesis found in other kinds of mammalian cells.",

author = "G. Agam and M. Djaldetti",

year = "1977",

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T1 - Inhibition of human platelet mitochondrial protein synthesis by chloramphenicol

AU - Agam, G.

AU - Djaldetti, M.

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AB - Human platelet mitochrondial protein synthesis, assayed by 'in vitro' 3H leucine incorporation into the protein moiety of isolated mitochondria, was shown to be inhibited by a therapeutic concentration of chloramphenical (CAP). This finding is in accordance with the ultrastructural damage caused to these organelles by the antibiotic, and with the inhibition of mitochondrial protein synthesis found in other kinds of mammalian cells.

UR - https://www.scopus.com/pages/publications/0017325844

M3 - Article

C2 - 861353

AN - SCOPUS:0017325844

SN - 0300-0885

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JO - Biomedicine Express

JF - Biomedicine Express

IS - 2

ER -

Inhibition of human platelet mitochondrial protein synthesis by chloramphenicol

Abstract

UN SDGs

ASJC Scopus subject areas

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