INO-8875, a highly selective A₁ adenosine receptor agonist: Evaluation of chronotropic, dromotropic, and hemodynamic effects in rats

Keyphrases

• Chronotropic Response 100%
• Hemodynamic Effects 100%
• Highly Selective 100%
• Adenosine A1 Receptor Agonist 100%
• Atrioventricular 100%
• A1 Receptor 40%
• Adenosine 40%
• Cardiovascular Effects 40%
• Arterial Blood Pressure 40%
• Duration of Action 40%
• Dose Effect 20%
• Receptor Agonist 20%
• Left Ventricular Function 20%
• Heart Rate 20%
• Electrophysiology 20%
• Functional Properties 20%
• Adult Rats 20%
• Riboside 20%
• Isolated Heart 20%
• Atrial Refractoriness 20%
• Pharmacological Activation 20%
• Functional Selectivity 20%
• 2-Aminopurine 20%
• Cardiovascular Profile 20%
• Dose-response Experiments 20%
• Coronary Resistance 20%

Neuroscience

• Receptor Agonists 100%
• Dromotropic 100%
• Chronotropic 100%
• Adenosine A1 Receptor 100%
• In Vivo 66%
• Adenosine 66%
• Eicosanoid Receptor 33%
• Agonist 33%
• Electrophysiology 33%
• Adenine 33%
• Functional Selectivity 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Side Effect 100%
• Adenosine 100%
• Adenosine A1 Receptor Agonist 100%
• Receptor 50%
• Clinical Study 50%
• Receptor Agonist 50%
• Adenine 50%
• Functional Selectivity 50%