Inositol may worsin attention deficit disorder with hyperactivity

Joseph Levine; Aliza Ring; Yoram Barak; Avner Elizur; R. H. Belmaker

doi:10.1002/hup.470100608

Inositol may worsin attention deficit disorder with hyperactivity

Joseph Levine, Aliza Ring, Yoram Barak, Avner Elizur, R. H. Belmaker

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Antidepressant drugs have been reported to improve ADDH symtomatology. Myoinositol is a simple isomer of glucose and is the precursor of the phosphatidylinositol second messenger system in brain. Both α₁‐adrenergic and 5HT₂ receptors activate this second messenger system. Recently, we found inositol to be effective in depression. Therefore we decided to evaluate the effects of oral inositol in children with ADDH in a double‐blind, cross‐over, placebo‐controlled manner. Eleven children, mean age 8.9 ± 3.6 years with a mean illness duration of 4.5 ± 2.8 years were enrolled in an 8‐week trial. Inositol or dextrose (placebo) was dispensed in powder form at a dose of 200 mg/kg aggravation of the syndrome with myo‐inositol as compared to placebo.

Original language	English
Pages (from-to)	481-484
Number of pages	4
Journal	Human Psychopharmacology
Volume	10
Issue number	6
DOIs	https://doi.org/10.1002/hup.470100608
State	Published - 1 Jan 1995

Keywords

attention deficit disorder with hyperactivity
inositol

ASJC Scopus subject areas

Neurology
Clinical Neurology
Psychiatry and Mental health
Pharmacology (medical)

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10.1002/hup.470100608

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AU - Ring, Aliza

AU - Barak, Yoram

AU - Elizur, Avner

AU - Belmaker, R. H.

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Inositol may worsin attention deficit disorder with hyperactivity

Abstract

Keywords

ASJC Scopus subject areas

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