Inositol-related gene knockouts mimic lithium's effect on mitochondrial function

Keyphrases

• Lithium 100%
• Inositol 100%
• Mitochondrial Function 100%
• Gene Knockout 100%
• Knock-in Mouse Model 33%
• Inositol Metabolism 25%
• Bipolar Disorder 16%
• Lithium Treatment 16%
• IMPA1 16%
• Bioinformatics Analysis 8%
• Behavioral Effects 8%
• Quantitative PCR 8%
• Wild Mice 8%
• Frontal Cortex 8%
• Differentially Expressed 8%
• DNA Microarray 8%
• Metabolic Alterations 8%
• Mitochondrial Dysfunction 8%
• Genetic Matching 8%
• Mitochondrial Genes 8%
• Inositol Depletion Hypothesis 8%
• Mitochondrial Electron Transport Chain 8%
• Phosphatidylinositol Signaling 8%
• Behavioral Phenotype 8%
• Forced Swim 8%
• Amphetamine-induced Hyperlocomotion 8%
• Lithium-mediated 8%
• Chronic Low Dose 8%
• Neurochemical Phenotype 8%
• Mitochondrial Respiratory Chain Complex I 8%
• Rotenone 8%
• Induced Behavior 8%
• Bioinformatics Approach 8%
• Microarray Assay 8%
• Complex I Inhibitor 8%

Neuroscience

• Mitochondrial Function 100%
• Inositol 100%
• Behavior (Neuroscience) 80%
• Metabolic Pathway 60%
• Bipolar Disorder 40%
• Electron Transport Chain 40%
• Behavioral Effect 20%
• Mitochondrion 20%
• Real-Time Polymerase Chain Reaction 20%
• Frontal Lobe 20%
• Phosphatidylinositol 20%
• DNA Microarray 20%
• Amphetamine 20%
• Rotenone 20%