Inositol treatment of Alzheimer's Disease: A double blind, cross-over placebo controlled trial

Yoram Barak; Joseph Levine; Arie Glasman; Avner Elizur; Robert H. Belmaker

doi:10.1016/0278-5846(96)00043-7

Inositol treatment of Alzheimer's Disease: A double blind, cross-over placebo controlled trial

Yoram Barak, Joseph Levine, Arie Glasman, Avner Elizur, Robert H. Belmaker

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

1. A double-blind controlled crossover trial of 6 gm of inositol daily vs glucose for one month each was carried out in 11 Alzheimer patients. 2. Overall CAMCOG scores showed a trend for greater improvement with inositol that was not significant. 3. Language and orientation improved significantly more on inositol than on placebo. There were no serious side effects. 4. Higher doses of inositol should be studied in Alzheimer's Disease for longer periods.

Original language	English
Pages (from-to)	729-735
Number of pages	7
Journal	Progress in Neuro-Psychopharmacology and Biological Psychiatry
Volume	20
Issue number	4
DOIs	https://doi.org/10.1016/0278-5846(96)00043-7
State	Published - 1 Jan 1996

Keywords

Alzheimer's disease
Inositol

ASJC Scopus subject areas

Pharmacology
Biological Psychiatry

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10.1016/0278-5846(96)00043-7

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AU - Elizur, Avner

AU - Belmaker, Robert H.

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N2 - 1. A double-blind controlled crossover trial of 6 gm of inositol daily vs glucose for one month each was carried out in 11 Alzheimer patients. 2. Overall CAMCOG scores showed a trend for greater improvement with inositol that was not significant. 3. Language and orientation improved significantly more on inositol than on placebo. There were no serious side effects. 4. Higher doses of inositol should be studied in Alzheimer's Disease for longer periods.

AB - 1. A double-blind controlled crossover trial of 6 gm of inositol daily vs glucose for one month each was carried out in 11 Alzheimer patients. 2. Overall CAMCOG scores showed a trend for greater improvement with inositol that was not significant. 3. Language and orientation improved significantly more on inositol than on placebo. There were no serious side effects. 4. Higher doses of inositol should be studied in Alzheimer's Disease for longer periods.

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Inositol treatment of Alzheimer's Disease: A double blind, cross-over placebo controlled trial

Abstract

Keywords

ASJC Scopus subject areas

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