Abstract
Cell biosensors have shown great potential for their use in various analytical applications, such as environmental monitoring and biomedical diagnostics. The main aspect of this field is the integration of live sensor cells into miniaturized hardware platforms that enable portability of the integrated system and improve its detection performance. Here, the authors review the (1) various hardware platform types that are used for cell biosensors; (2) sensor cell immobilization strategies onto these platforms; (3) transduction mechanisms of the biological response to a bioelectronic signal; and (4) modeling of the sensor cell-hardware platform bioelectronic interface.
Original language | English |
---|---|
Title of host publication | Handbook of Cell Biosensors |
Publisher | Springer International Publishing |
Pages | 141-162 |
Number of pages | 22 |
ISBN (Electronic) | 9783030232177 |
ISBN (Print) | 9783030232160 |
DOIs | |
State | Published - 1 Jan 2021 |
Keywords
- Bio-interface
- Bio-microelectromechanical systems
- Biochip
- Bioelectronics
- Biomedical diagnostics
- Cell immobilization
- Integrated cell-based biosensors
- Microfabrication
- Physicochemical transducers
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology
- General Medicine