Integration of Sensor Cells into Hardware Platforms

Rajendra P. Shukla, Avia Lavon, Hadar Ben-Yoav

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Cell biosensors have shown great potential for their use in various analytical applications, such as environmental monitoring and biomedical diagnostics. The main aspect of this field is the integration of live sensor cells into miniaturized hardware platforms that enable portability of the integrated system and improve its detection performance. Here, the authors review the (1) various hardware platform types that are used for cell biosensors; (2) sensor cell immobilization strategies onto these platforms; (3) transduction mechanisms of the biological response to a bioelectronic signal; and (4) modeling of the sensor cell-hardware platform bioelectronic interface.

Original languageEnglish
Title of host publicationHandbook of Cell Biosensors
PublisherSpringer International Publishing
Pages141-162
Number of pages22
ISBN (Electronic)9783030232177
ISBN (Print)9783030232160
DOIs
StatePublished - 1 Jan 2021

Keywords

  • Bio-interface
  • Bio-microelectromechanical systems
  • Biochip
  • Bioelectronics
  • Biomedical diagnostics
  • Cell immobilization
  • Integrated cell-based biosensors
  • Microfabrication
  • Physicochemical transducers

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Medicine

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