Intelligent multi-sensor arrays for next generation diagnostic biodevices

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Redox molecules play an essential role in many biological pathways, including energy metabolism, biosynthesis, and cell respiration. Moreover, a specific spectrum of redox molecules (comprising their type, concentration, and redox state) is involved in the development of diseases, including cancer. Thus, profiling the redox spectrum in the body is highly beneficial for a wide range of biomedical applications, from in vivo diagnostics to in situ monitoring of cell metabolism. Yet, the fundamental challenge lies within the ability to efficiently extract and analyze physiologically and medically relevant information from redox molecules in biofluids. This paper will discuss the advantageous approach to rapidly and continuously monitor redox molecules in biofluids using electrochemical lab-on-a-chip biodevices. The current approaches will be discussed to selectively measure redox molecules from biofluids without diminishing the rapid and continuous monitoring capabilities of these translational biodevices, i.e., by simultaneously analyzing multiple diagnostic redox biomarkers in a stand-alone operation, without any sample pretreatment or elimination of other interfering molecules. Then, the promising approach of using intelligent multi-sensor arrays will be highlighted for the rapid detection of a spectrum of redox molecules and the current challenges impeding their important utilization for next generation biomedical diagnostic devices.

Original languageEnglish
Title of host publicationBIODEVICES 2018 - 11th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 11th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2018
EditorsAlberto Cliquet, Alberto Cliquet, Hugo Gamboa, Ana Fred, Sergi Bermudez i Badia
PublisherSciTePress
Pages236-240
Number of pages5
ISBN (Electronic)9789897582776
DOIs
StatePublished - 1 Jan 2018
Event11th International Conference on Biomedical Electronics and Devices, BIODEVICES 2018 - Part of 11th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2018 - Funchal, Madeira, Portugal
Duration: 19 Jan 201821 Jan 2018

Publication series

NameBIODEVICES 2018 - 11th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 11th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2018
Volume1

Conference

Conference11th International Conference on Biomedical Electronics and Devices, BIODEVICES 2018 - Part of 11th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2018
Country/TerritoryPortugal
CityFunchal, Madeira
Period19/01/1821/01/18

Keywords

  • Biomedical Diagnostics
  • Chemometrics
  • Electrochemical Sensors
  • Intelligent Sensors
  • Lab-on-a-Chip
  • Redox

Fingerprint

Dive into the research topics of 'Intelligent multi-sensor arrays for next generation diagnostic biodevices'. Together they form a unique fingerprint.

Cite this