Interferon-alpha induced autoimmune hepatitis in a patient with Philadelphia chromosome-positive chronic myeloid leukemia with cytogenetically normal T lymphocytes.

S. Ariad; E. Song; R. Cohen; W. R. Bezwoda

Interferon-alpha induced autoimmune hepatitis in a patient with Philadelphia chromosome-positive chronic myeloid leukemia with cytogenetically normal T lymphocytes.

S. Ariad
, E. Song
, R. Cohen
, W. R. Bezwoda

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

We report the occurrence of autoimmune hepatitis after treatment with interferon-alpha in a patient with Philadelphia chromosome-positive chronic myeloid leukemia. Cytogenetic and molecular genetic studies of the T lymphocytes in this patient demonstrated that the T lymphocytes were not part of the leukemic clone. The role of interferon in the production of autoimmune abnormalities is reviewed.

Original language	English
Pages (from-to)	139-142
Number of pages	4
Journal	Molecular biotherapy
Volume	4
Issue number	3
State	Published - 1 Jan 1992
Externally published	Yes

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title = "Interferon-alpha induced autoimmune hepatitis in a patient with Philadelphia chromosome-positive chronic myeloid leukemia with cytogenetically normal T lymphocytes.",

abstract = "We report the occurrence of autoimmune hepatitis after treatment with interferon-alpha in a patient with Philadelphia chromosome-positive chronic myeloid leukemia. Cytogenetic and molecular genetic studies of the T lymphocytes in this patient demonstrated that the T lymphocytes were not part of the leukemic clone. The role of interferon in the production of autoimmune abnormalities is reviewed.",

author = "S. Ariad and E. Song and R. Cohen and Bezwoda, \{W. R.\}",

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AU - Ariad, S.

AU - Song, E.

AU - Cohen, R.

AU - Bezwoda, W. R.

PY - 1992/1/1

Y1 - 1992/1/1

N2 - We report the occurrence of autoimmune hepatitis after treatment with interferon-alpha in a patient with Philadelphia chromosome-positive chronic myeloid leukemia. Cytogenetic and molecular genetic studies of the T lymphocytes in this patient demonstrated that the T lymphocytes were not part of the leukemic clone. The role of interferon in the production of autoimmune abnormalities is reviewed.

AB - We report the occurrence of autoimmune hepatitis after treatment with interferon-alpha in a patient with Philadelphia chromosome-positive chronic myeloid leukemia. Cytogenetic and molecular genetic studies of the T lymphocytes in this patient demonstrated that the T lymphocytes were not part of the leukemic clone. The role of interferon in the production of autoimmune abnormalities is reviewed.

UR - https://www.scopus.com/pages/publications/0026928282

M3 - Article

C2 - 1445668

AN - SCOPUS:0026928282

SN - 0952-8172

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JO - Molecular biotherapy

JF - Molecular biotherapy

IS - 3

ER -

Interferon-alpha induced autoimmune hepatitis in a patient with Philadelphia chromosome-positive chronic myeloid leukemia with cytogenetically normal T lymphocytes.

Abstract

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