Interleukin-2 production by human pre-implantation embryos

R. Orvieto; I. Bar-Hava; A. Schwartz; M. Shelef; Z. Ben-Rafael

doi:10.3109/09513599709152557

Interleukin-2 production by human pre-implantation embryos

R. Orvieto, I. Bar-Hava, A. Schwartz, M. Shelef, Z. Ben-Rafael

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The study was conducted to determine whether pre-implantation embryos secrete interleukin-2. Conditioned media of 27 embryos derived from women during in vitro fertilization (IVF) cycles were analyzed for interleukin-2 concentration. The results showed that conditioned embryo medium from the two pronuclei stage of 24 hours later contains interleukin-2. Endometrial large granular lymphocytes, which are probably involved in placentation, replicate in response to interleukin-2. It may therefore be speculated that interleukin-2 secreted by human embryos may modulate the function and replication of large granular lymphocytes.

Original language	English
Pages (from-to)	331-334
Number of pages	4
Journal	Gynecological Endocrinology
Volume	11
Issue number	5
DOIs	https://doi.org/10.3109/09513599709152557
State	Published - 1 Jan 1997
Externally published	Yes

Keywords

In vitro fertilization
Interleukin-2
Pre-implantation embryos

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Obstetrics and Gynecology

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abstract = "The study was conducted to determine whether pre-implantation embryos secrete interleukin-2. Conditioned media of 27 embryos derived from women during in vitro fertilization (IVF) cycles were analyzed for interleukin-2 concentration. The results showed that conditioned embryo medium from the two pronuclei stage of 24 hours later contains interleukin-2. Endometrial large granular lymphocytes, which are probably involved in placentation, replicate in response to interleukin-2. It may therefore be speculated that interleukin-2 secreted by human embryos may modulate the function and replication of large granular lymphocytes.",

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AU - Orvieto, R.

AU - Bar-Hava, I.

AU - Schwartz, A.

AU - Shelef, M.

AU - Ben-Rafael, Z.

PY - 1997/1/1

Y1 - 1997/1/1

N2 - The study was conducted to determine whether pre-implantation embryos secrete interleukin-2. Conditioned media of 27 embryos derived from women during in vitro fertilization (IVF) cycles were analyzed for interleukin-2 concentration. The results showed that conditioned embryo medium from the two pronuclei stage of 24 hours later contains interleukin-2. Endometrial large granular lymphocytes, which are probably involved in placentation, replicate in response to interleukin-2. It may therefore be speculated that interleukin-2 secreted by human embryos may modulate the function and replication of large granular lymphocytes.

AB - The study was conducted to determine whether pre-implantation embryos secrete interleukin-2. Conditioned media of 27 embryos derived from women during in vitro fertilization (IVF) cycles were analyzed for interleukin-2 concentration. The results showed that conditioned embryo medium from the two pronuclei stage of 24 hours later contains interleukin-2. Endometrial large granular lymphocytes, which are probably involved in placentation, replicate in response to interleukin-2. It may therefore be speculated that interleukin-2 secreted by human embryos may modulate the function and replication of large granular lymphocytes.

KW - In vitro fertilization

KW - Interleukin-2

KW - Pre-implantation embryos

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JO - Gynecological Endocrinology

JF - Gynecological Endocrinology

IS - 5

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Interleukin-2 production by human pre-implantation embryos

Abstract

Keywords

ASJC Scopus subject areas

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