Interleukin-6 release following scorpion sting in children

Shaul Sofer; Mosche Gueron; Rosalyn M. White; Matitihau Lifshitz; Ron N. Apte

doi:10.1016/0041-0101(95)00136-0

Interleukin-6 release following scorpion sting in children

Shaul Sofer, Mosche Gueron, Rosalyn M. White, Matitihau Lifshitz, Ron N. Apte

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Abstract

Interleukin-6 levels were measured in the serum of ten children following severe scorpion envenomation. Measurements were taken on arrival, at the emergency room, and 12 and 24 hr after arrival. Interleukin-6 was markedly elevated in the serum of eight out of ten children on arrival. Interleukin-6 levels gradually decreased toward normal values on 12 and 24 hr measurements, but remained above control levels on all measurements. These results imply that signs and symptoms following scorpion envenomation may in part be explained by release of cytokines. Human and experimental animal studies are required in order to verify the assumption that interleukin-6 and other cytokines are involved in the pathogenesis of scorpion envenomation.

Original language	English
Pages (from-to)	389-392
Number of pages	4
Journal	Toxicon
Volume	34
Issue number	3
DOIs	https://doi.org/10.1016/0041-0101(95)00136-0
State	Published - 1 Jan 1996

ASJC Scopus subject areas

Toxicology

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10.1016/0041-0101(95)00136-0

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title = "Interleukin-6 release following scorpion sting in children",

abstract = "Interleukin-6 levels were measured in the serum of ten children following severe scorpion envenomation. Measurements were taken on arrival, at the emergency room, and 12 and 24 hr after arrival. Interleukin-6 was markedly elevated in the serum of eight out of ten children on arrival. Interleukin-6 levels gradually decreased toward normal values on 12 and 24 hr measurements, but remained above control levels on all measurements. These results imply that signs and symptoms following scorpion envenomation may in part be explained by release of cytokines. Human and experimental animal studies are required in order to verify the assumption that interleukin-6 and other cytokines are involved in the pathogenesis of scorpion envenomation.",

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T1 - Interleukin-6 release following scorpion sting in children

AU - Sofer, Shaul

AU - Gueron, Mosche

AU - White, Rosalyn M.

AU - Lifshitz, Matitihau

AU - Apte, Ron N.

PY - 1996/1/1

Y1 - 1996/1/1

N2 - Interleukin-6 levels were measured in the serum of ten children following severe scorpion envenomation. Measurements were taken on arrival, at the emergency room, and 12 and 24 hr after arrival. Interleukin-6 was markedly elevated in the serum of eight out of ten children on arrival. Interleukin-6 levels gradually decreased toward normal values on 12 and 24 hr measurements, but remained above control levels on all measurements. These results imply that signs and symptoms following scorpion envenomation may in part be explained by release of cytokines. Human and experimental animal studies are required in order to verify the assumption that interleukin-6 and other cytokines are involved in the pathogenesis of scorpion envenomation.

AB - Interleukin-6 levels were measured in the serum of ten children following severe scorpion envenomation. Measurements were taken on arrival, at the emergency room, and 12 and 24 hr after arrival. Interleukin-6 was markedly elevated in the serum of eight out of ten children on arrival. Interleukin-6 levels gradually decreased toward normal values on 12 and 24 hr measurements, but remained above control levels on all measurements. These results imply that signs and symptoms following scorpion envenomation may in part be explained by release of cytokines. Human and experimental animal studies are required in order to verify the assumption that interleukin-6 and other cytokines are involved in the pathogenesis of scorpion envenomation.

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DO - 10.1016/0041-0101(95)00136-0

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EP - 392

JO - Toxicon

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Interleukin-6 release following scorpion sting in children

Abstract

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