TY - JOUR
T1 - Intervention modalities for targeting cognitive-motor interference in individuals with neurodegenerative disease
T2 - a systematic review
AU - Wajda, Douglas A.
AU - Mirelman, Anat
AU - Hausdorff, Jeffrey M.
AU - Sosnoff, Jacob J.
N1 - Publisher Copyright:
© 2016 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2017/3/4
Y1 - 2017/3/4
N2 - Introduction: Individuals with neurodegenerative disease (NDD) commonly have elevated cognitive-motor interference, change in either cognitive or motor performance (or both) when tasks are performed simultaneously, compared to healthy controls. Given that cognitive-motor interference is related to reduced community ambulation and elevated fall risk, it is a target of rehabilitation interventions. Areas covered: This review details the collective findings of previous dual task interventions in individuals with NDD. A total of 21 investigations focusing on 4 different neurodegenerative diseases and one NDD precursor (Parkinson’s disease, multiple sclerosis, Alzheimer’s disease (AD), dementia other than AD, and mild cognitive impairment) consisting of 721 participants were reviewed. Expert commentary: Preliminary evidence from interventions targeting cognitive-motor interference, both directly and indirectly, show promising results for improving CMI in individuals with neurodegenerative diseases. Methodological limitations, common to pilot investigations preclude firm conclusions. Well-designed randomized control trials targeting cognitive motor interference are warranted.
AB - Introduction: Individuals with neurodegenerative disease (NDD) commonly have elevated cognitive-motor interference, change in either cognitive or motor performance (or both) when tasks are performed simultaneously, compared to healthy controls. Given that cognitive-motor interference is related to reduced community ambulation and elevated fall risk, it is a target of rehabilitation interventions. Areas covered: This review details the collective findings of previous dual task interventions in individuals with NDD. A total of 21 investigations focusing on 4 different neurodegenerative diseases and one NDD precursor (Parkinson’s disease, multiple sclerosis, Alzheimer’s disease (AD), dementia other than AD, and mild cognitive impairment) consisting of 721 participants were reviewed. Expert commentary: Preliminary evidence from interventions targeting cognitive-motor interference, both directly and indirectly, show promising results for improving CMI in individuals with neurodegenerative diseases. Methodological limitations, common to pilot investigations preclude firm conclusions. Well-designed randomized control trials targeting cognitive motor interference are warranted.
KW - Dual task
KW - cognitive-motor
KW - neurodegenerative disease
KW - training
KW - virtual reality
UR - http://www.scopus.com/inward/record.url?scp=85013220241&partnerID=8YFLogxK
U2 - 10.1080/14737175.2016.1227704
DO - 10.1080/14737175.2016.1227704
M3 - Review article
AN - SCOPUS:85013220241
SN - 1473-7175
VL - 17
SP - 251
EP - 261
JO - Expert Review of Neurotherapeutics
JF - Expert Review of Neurotherapeutics
IS - 3
ER -