Intracellular transport of agrobacterium T-DNA

Benoît Lacroix, Michael Elbaum, Vitaly Citovsky, Tzvi Tzfira

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

4 Scopus citations

Abstract

To transfer genes to plants or other organisms, Agrobacterium exports its transferred DNA (T-DNA), along with several virulence proteins, into the host cell. The T-DNA must then be transported through the cytoplasm to the nuclear pore, pass through the nuclear pore complex, and finally move inside the nucleus toward a potential site of integration into the host genome. This T-DNA voyage inside the host cell results from a complex interplay between numerous bacterial and host factors, where host-cell machineries that allow macromolecular movements are employed by Agrobacterium to achieve the transfer and integration of T-DNA into the host genome.

Original languageEnglish
Title of host publicationAgrobacterium
Subtitle of host publicationFrom Biology to Biotechnology
PublisherSpringer New York
Pages365-394
Number of pages30
ISBN (Print)9780387722894
DOIs
StatePublished - 1 Dec 2008
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (all)
  • Agricultural and Biological Sciences (all)

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