Intrathecal Baclofen Therapy—Practical Approach: Clinical Benefits and Complication Management

Gidon Winter, Liana Beni-Adani, Hilla Ben-Pazi

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations


Intrathecal baclofen is an expanding accepted treatment for children with cerebral palsy and other causes of spasticity and dystonia. The aims of this review are therefore to (1) delineate the clinical benefits of intrathecal baclofen therapy in pediatric spasticity and dystonia and (2) increase awareness of the potential complications and emergency management measures of intrathecal baclofen therapy. A current literature review demonstrates the benefits and complications of this minimally invasive device. Practical guides for recognizing acute conditions and management recommendations are included. Intrathecal baclofen is increasingly being used to help individuals attain realistic functional goals. Therefore, families and health care professionals should be aware of potential complications, symptoms, and emergency management.

Original languageEnglish
Pages (from-to)734-741
Number of pages8
JournalJournal of Child Neurology
Issue number11
StatePublished - 1 Oct 2018
Externally publishedYes


  • cerebral palsy
  • dystonia
  • intrathecal baclofen
  • overdose
  • spasticity
  • withdrawal

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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