Intravenous immunoglobulin for immunomodulation of systemic lupus erythematosus

Yaniv Sherer, Yehuda Shoenfeld

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Intravenous immunoglobulin (IVIg) is used for replacement therapy in immunodeficiency states and for immunomodulation of various autoimmune diseases. Several case reports and series support a beneficial role of IVIg in systemic lupus erythematosus (SLE), both as salvage immunotherapy and in control of disease activity in general and amelioration of classical disease manifestations. Further, lupus nephritis can also be treated usually successfully with IVIg. A few questions remain unanswered as to the appropriate therapeutic dosage and the clinical manifestations that can be best treated with IVIg.

Original languageEnglish
Pages (from-to)153-155
Number of pages3
JournalAutoimmunity Reviews
Volume5
Issue number2 SPEC. ISS.
DOIs
StatePublished - 1 Jan 2006
Externally publishedYes

Keywords

  • Immunomodulation
  • Intravenous immunoglobulin
  • Systemic lupus erythematosus

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