Intravenous methylphenidate: An unusual way to provoke ST-elevation myocardial infarction

Emile Hay, Vitaly Shklovski, Yossef Blaer, Vladimir Shlakhover, Amos Katz

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Acute ST-T elevation is a sign of myocardial ischemia or infarction usually due to coronary artery atherosclerosis or coronary spasm. Coronary spasm may be spontaneous or can occur as a result of a drug that causes arterial spam. Ritalin, Novartis Pharmaceut. Corporation, USA (methylphenidate hydrochloride), a dopamine reuptake inhibitor, is an oral drug used to treat attention-deficit/hyperactivity disorder and narcolepsy. Sudden deaths, stroke, and myocardial infarction have been reported in adults taking stimulant drugs at usual dose for attention-deficit/hyperactivity disorder [1]. This drug is not supplied as solution for injection [2]. We report here, what we believe to be, the first case report of a 40-year-old male patient who was admitted for acute chest pain and ST-elevation myocardial infarction after intravenous self-injection of Ritalin. His coronary angiogram demonstrated nonobstructive coronary disease.

Original languageEnglish
Article number54424
Pages (from-to)313.e1-313.e3
JournalAmerican Journal of Emergency Medicine
Issue number2
StatePublished - 1 Feb 2015

ASJC Scopus subject areas

  • Emergency Medicine


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