Intrinsic Fluorescence Polarization of Amniotic Fluid: Evaluation of Human Fetal Lung Maturity

Jonathan Molcho, Hemy Avraham, Rivka Cohen-Luria, Abraham H. Parola

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

This article reports a novel approach for the evaluation of fetal lung maturity based on fluorescence polarization (FP). The technique determines the intrinsic fluorescence polarization ratio (IFPR) of the amniotic fluid (AF). In vitro measurements of the IFPR indicate a clear dichotomy: high values for young pregnancies and low values for mature pregnancies. The new method has the potential to be a non-invasive procedure because the excitation of the AF and the collection of its fluorescence emission can be performed through the intact cervical amniotic membranes.

Original languageEnglish
Pages (from-to)105-108
Number of pages4
JournalPhotochemistry and Photobiology
Volume78
Issue number2
DOIs
StatePublished - 1 Aug 2003

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry

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