Investigating the Binding Mode of an Inhibitor of the MBNL1{dot operator}RNA Complex in Myotonic Dystrophy Type 1 (DM1) Leads to the Unexpected Discovery of a DNA-Selective Binder

Chun Ho Wong; Stacie L. Richardson; Yen Jun Ho; Alex M.H. Lucas; Tiziano Tuccinardi; Anne M. Baranger; Steven C. Zimmerman

doi:10.1002/cbic.201200602

Investigating the Binding Mode of an Inhibitor of the MBNL1{dot operator}RNA Complex in Myotonic Dystrophy Type 1 (DM1) Leads to the Unexpected Discovery of a DNA-Selective Binder

Chun Ho Wong
, Stacie L. Richardson
, Yen Jun Ho
, Alex M.H. Lucas
, Tiziano Tuccinardi
, Anne M. Baranger
, Steven C. Zimmerman

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Original language	English
Pages (from-to)	2505-2509
Number of pages	5
Journal	ChemBioChem
Volume	13
Issue number	17
DOIs	https://doi.org/10.1002/cbic.201200602
State	Published - 1 Nov 2012
Externally published	Yes

Keywords

DNA
Drug design
Inhibitors
RNA
Recognition

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/cbic.201200602

Cite this

Wong, C. H., Richardson, S. L., Ho, Y. J., Lucas, A. M. H., Tuccinardi, T., Baranger, A. M., & Zimmerman, S. C. (2012). Investigating the Binding Mode of an Inhibitor of the MBNL1{dot operator}RNA Complex in Myotonic Dystrophy Type 1 (DM1) Leads to the Unexpected Discovery of a DNA-Selective Binder. ChemBioChem, 13(17), 2505-2509. https://doi.org/10.1002/cbic.201200602

@article{f77e491a14fd4cd4ad3f3843324c3a9f,

title = "Investigating the Binding Mode of an Inhibitor of the MBNL1\{dot operator\}RNA Complex in Myotonic Dystrophy Type 1 (DM1) Leads to the Unexpected Discovery of a DNA-Selective Binder",

keywords = "DNA, Drug design, Inhibitors, RNA, Recognition",

author = "Wong, \{Chun Ho\} and Richardson, \{Stacie L.\} and Ho, \{Yen Jun\} and Lucas, \{Alex M.H.\} and Tiziano Tuccinardi and Baranger, \{Anne M.\} and Zimmerman, \{Steven C.\}",

year = "2012",

month = nov,

day = "1",

doi = "10.1002/cbic.201200602",

language = "English",

volume = "13",

pages = "2505--2509",

journal = "ChemBioChem",

issn = "1439-4227",

publisher = "John Wiley and Sons Inc.",

number = "17",

}

TY - JOUR

T1 - Investigating the Binding Mode of an Inhibitor of the MBNL1{dot operator}RNA Complex in Myotonic Dystrophy Type 1 (DM1) Leads to the Unexpected Discovery of a DNA-Selective Binder

AU - Wong, Chun Ho

AU - Richardson, Stacie L.

AU - Ho, Yen Jun

AU - Lucas, Alex M.H.

AU - Tuccinardi, Tiziano

AU - Baranger, Anne M.

AU - Zimmerman, Steven C.

PY - 2012/11/1

Y1 - 2012/11/1

KW - DNA

KW - Drug design

KW - Inhibitors

KW - RNA

KW - Recognition

UR - https://www.scopus.com/pages/publications/84869411946

U2 - 10.1002/cbic.201200602

DO - 10.1002/cbic.201200602

M3 - Article

C2 - 23097190

AN - SCOPUS:84869411946

SN - 1439-4227

VL - 13

SP - 2505

EP - 2509

JO - ChemBioChem

JF - ChemBioChem

IS - 17

ER -

Investigating the Binding Mode of an Inhibitor of the MBNL1{dot operator}RNA Complex in Myotonic Dystrophy Type 1 (DM1) Leads to the Unexpected Discovery of a DNA-Selective Binder

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Cite this