Ir(III)-Catalyzed Carbenoid Functionalization of Benzamides: Synthesis of N-Methoxyisoquinolinediones and N-Methoxyisoquinolinones

Ravindra S. Phatake, Pitambar Patel, Chepuri V. Ramana

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

A mild and efficient Ir(III)-catalyzed C-H carbenoid functionalization strategy has been developed to access N-methoxyisoquinolinediones and N-methoxyisoquinolinones. The reaction proceeds efficiently in high yield at room temperature over a broad range of substrates without requirement of any additional oxidants or a base.

Original languageEnglish
Pages (from-to)2828-2831
Number of pages4
JournalOrganic Letters
Volume18
Issue number12
DOIs
StatePublished - 17 Jun 2016
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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