Is bone marrow biopsy obligatory in all patients with non-Hodgkin's lymphoma?

Osnat Bairey, Ofer Shpilberg

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Bone marrow biopsy (BMB) is recommended as a part of the workup diagnosis in all patients with non-Hodgkin's lymphoma (NHL). This is an invasive procedure that is mostly stressful for the patient and very rarely is associated with severe bleeding. We suggest that the clinician needs to weigh up the potential benefit of this procedure in each case in terms of changing therapeutic approach and prognosis. We think BMB is not mandatory in every patient with NHL and suggest recommendations for which patients we should continue to perform this procedure on.

Original languageEnglish
Pages (from-to)61-64
Number of pages4
JournalActa Haematologica
Issue number1
StatePublished - 1 Jun 2007


  • Aggressive lymphoma
  • Bone-marrow biopsy
  • Extranodal
  • Indolent lymphoma
  • International Prognostic Index
  • Non-Hodgkin's lymphoma
  • Stage

ASJC Scopus subject areas

  • Hematology


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