Is induction of labor risky for twins compare to singleton pregnancies?

Rania Okby, Ilana Shoham-Vardi, Sergienko Ruslan, Eyal Sheiner

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Objective: The aim of this study was to investigate whether induction of labor in twin pregnancies is associated with higher rates of maternal complications as compared to singletons. Method: A retrospective population-based study was conducted to compare maternal complications following induction of labor in twin pregnancies and singletons at Soroka University Medical Center, Be'er-Sheva, Israel, between 1988 and 2010. Stratified analysis using a multiple logistic regression model was performed to control for confounders. Results: The study population included 25913 patients following induction of labor, of these 191 (0.73%) were in twin pregnancies. Induction of labor in twin pregnancies was not associated with adverse maternal outcomes such as cervical tears, third degree perineal tears, uterine rupture, peripartum hysterectomy, post-partum hemorrhage or retained placenta. However, labor induction in twins was significantly associated with cesarean deliveries (31.2% versus 17.1%; p<0.001). Using a multivariable analysis controlling for confounders, induction at twins was an independent risk factor for cesarean delivery (CD; adjusted OR=2.2, 95% CI 1.7-2.7, p<0.001). Conclusion: Induction of labor in twin pregnancies does not increase the risk for maternal complications. However, it is an independent risk factor for CD.

Original languageEnglish
Pages (from-to)1804-1806
Number of pages3
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume26
Issue number18
DOIs
StatePublished - 1 Dec 2013

Keywords

  • Cesarean delivery
  • Induction of labor
  • PPH
  • Twin pregnancy
  • Uterine rupture

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