TY - JOUR
T1 - Is there an association between a history of placental abruption and long-term maternal renal complications?
AU - Arazi, E. S.
AU - Kessous, R.
AU - Shoham-Vardi, I.
AU - Pariente, G.
AU - Sergienko, R.
AU - Sheiner, Eyal
N1 - Publisher Copyright:
© 2014 Informa UK Ltd. All rights reserved.
PY - 2015/9/22
Y1 - 2015/9/22
N2 - Objective: To investigate whether patients with a history of placental abruption have an increased risk for subsequent maternal long-term morbidity. Study design: A population-based study compared the incidence of long-term renal morbidity in cohort of women with and without a history of placental abruption. Deliveries occurred during a 25-year period, with a mean follow-up duration of 11.2 years. Renal morbidity included kidney transplantation, chronic renal failure, hypertensive renal disease, etc. Results: During the study period 99 354 deliveries met the inclusion criteria; 1.8% (n = 1807) occurred in patients with a diagnosis of placental abruption. Patients with placental abruption did not have higher cumulative incidence of renal related hospitalizations, using Kaplan-Meier survival curve. During the follow-up period patients with a history of placental abruption did not have higher rate of renal morbidity (0.2% versus 0.1%; OR 1.8; 95% CI 0.6-4.8; p = 0.261). When performing a Cox proportional hazards model, adjusted for confounders such as parity and diabetes mellitus, a history of placental abruption was not associated with renal related hospitalizations (adjusted HR, 1.6; 95% CI, 0.6-4.2; p = 0.381). Conclusion: Placental abruption, even though considered a part of the "placental syndrome" with possible vascular etiology, is not a risk factor for long-term maternal renal complications.
AB - Objective: To investigate whether patients with a history of placental abruption have an increased risk for subsequent maternal long-term morbidity. Study design: A population-based study compared the incidence of long-term renal morbidity in cohort of women with and without a history of placental abruption. Deliveries occurred during a 25-year period, with a mean follow-up duration of 11.2 years. Renal morbidity included kidney transplantation, chronic renal failure, hypertensive renal disease, etc. Results: During the study period 99 354 deliveries met the inclusion criteria; 1.8% (n = 1807) occurred in patients with a diagnosis of placental abruption. Patients with placental abruption did not have higher cumulative incidence of renal related hospitalizations, using Kaplan-Meier survival curve. During the follow-up period patients with a history of placental abruption did not have higher rate of renal morbidity (0.2% versus 0.1%; OR 1.8; 95% CI 0.6-4.8; p = 0.261). When performing a Cox proportional hazards model, adjusted for confounders such as parity and diabetes mellitus, a history of placental abruption was not associated with renal related hospitalizations (adjusted HR, 1.6; 95% CI, 0.6-4.2; p = 0.381). Conclusion: Placental abruption, even though considered a part of the "placental syndrome" with possible vascular etiology, is not a risk factor for long-term maternal renal complications.
KW - Obstetric complication
KW - placental abruption
KW - renal morbidity
UR - http://www.scopus.com/inward/record.url?scp=84941053546&partnerID=8YFLogxK
U2 - 10.3109/14767058.2014.967206
DO - 10.3109/14767058.2014.967206
M3 - Article
C2 - 25234099
AN - SCOPUS:84941053546
VL - 28
SP - 1641
EP - 1646
JO - Journal of Maternal-Fetal and Neonatal Medicine
JF - Journal of Maternal-Fetal and Neonatal Medicine
SN - 1476-7058
IS - 14
ER -