Isolated ACTH deficiency and primary hypothyroidism: Volume-dependent elevation of antidiuretic hormone secretion in the presence of hyponatremia

D. Leroith; D. Broitman; S. Sukenik; S. M. Glick

Isolated ACTH deficiency and primary hypothyroidism: Volume-dependent elevation of antidiuretic hormone secretion in the presence of hyponatremia

D. Leroith, D. Broitman, S. Sukenik, S. M. Glick

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9 Scopus citations

Abstract

The unusual combination of isolated deficiency of ACTH secretion and primary hypothyroidism was demonstrated in a 72-year-old man. Antidiuretic hormone (ADH) levels were elevated despite severe hyponatremia. This abnormality was corrected by salt replacement and hydrocortisone therapy. These results suggest that the elevated ADH levels were appropriate for the volume depletion caused by the hypoadrenalism and were not related to the hypothyroidism.

Original language	English
Pages (from-to)	440-443
Number of pages	4
Journal	Israel Journal of Medical Sciences
Volume	16
Issue number	6
State	Published - 1 Jan 1980
Externally published	Yes

ASJC Scopus subject areas

Bioengineering

Cite this

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title = "Isolated ACTH deficiency and primary hypothyroidism: Volume-dependent elevation of antidiuretic hormone secretion in the presence of hyponatremia",

abstract = "The unusual combination of isolated deficiency of ACTH secretion and primary hypothyroidism was demonstrated in a 72-year-old man. Antidiuretic hormone (ADH) levels were elevated despite severe hyponatremia. This abnormality was corrected by salt replacement and hydrocortisone therapy. These results suggest that the elevated ADH levels were appropriate for the volume depletion caused by the hypoadrenalism and were not related to the hypothyroidism.",

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AU - Broitman, D.

AU - Sukenik, S.

AU - Glick, S. M.

PY - 1980/1/1

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N2 - The unusual combination of isolated deficiency of ACTH secretion and primary hypothyroidism was demonstrated in a 72-year-old man. Antidiuretic hormone (ADH) levels were elevated despite severe hyponatremia. This abnormality was corrected by salt replacement and hydrocortisone therapy. These results suggest that the elevated ADH levels were appropriate for the volume depletion caused by the hypoadrenalism and were not related to the hypothyroidism.

AB - The unusual combination of isolated deficiency of ACTH secretion and primary hypothyroidism was demonstrated in a 72-year-old man. Antidiuretic hormone (ADH) levels were elevated despite severe hyponatremia. This abnormality was corrected by salt replacement and hydrocortisone therapy. These results suggest that the elevated ADH levels were appropriate for the volume depletion caused by the hypoadrenalism and were not related to the hypothyroidism.

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M3 - Article

AN - SCOPUS:0018853428

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JO - Israel Medical Association Journal

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Isolated ACTH deficiency and primary hypothyroidism: Volume-dependent elevation of antidiuretic hormone secretion in the presence of hyponatremia

Abstract

ASJC Scopus subject areas

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