Isolated congenital histiocytosis in the palpebral conjunctiva in a newborn.

Tova Monos, Jaime Levy, Tova Lifshitz, Ronit Yagev, Esther Maor

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


PURPOSE: To report a rare case of congenital histiocytosis in a newborn without skin involvement. DESIGN: Interventional case-report. METHODS: A full-term baby presented with a mass over the palpebral conjunctiva of his left upper lid. Ophthalmic examination was otherwise normal, and the baby was healthy. There were no skin lesions. RESULTS: The lesion was completely removed surgically. Pathologic examination demonstrated a cellular infiltrate composed of eosinophils and histiocytes. Immunohistochemistry disclosed positive stain for protein S-100 and CD1 antigenic determinant. Pediatric oncology evaluation was completely normal. Eighteen months after presentation, the patient remained healthy without recurrence of the lesion. CONCLUSIONS: Rare cases of congenital histiocytosis can present as a solitary lesion over the palpebral conjunctiva, without skin or systemic involvement.

Original languageEnglish
Pages (from-to)728-730
Number of pages3
JournalAmerican Journal of Ophthalmology
Issue number4
StatePublished - 1 Jan 2005
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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