Isolated congenital histiocytosis in the palpebral conjunctiva in a newborn.

Tova Monos; Jaime Levy; Tova Lifshitz; Ronit Yagev; Esther Maor

doi:10.1016/j.ajo.2004.10.001

Isolated congenital histiocytosis in the palpebral conjunctiva in a newborn.

Tova Monos, Jaime Levy, Tova Lifshitz, Ronit Yagev, Esther Maor

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

PURPOSE: To report a rare case of congenital histiocytosis in a newborn without skin involvement. DESIGN: Interventional case-report. METHODS: A full-term baby presented with a mass over the palpebral conjunctiva of his left upper lid. Ophthalmic examination was otherwise normal, and the baby was healthy. There were no skin lesions. RESULTS: The lesion was completely removed surgically. Pathologic examination demonstrated a cellular infiltrate composed of eosinophils and histiocytes. Immunohistochemistry disclosed positive stain for protein S-100 and CD1 antigenic determinant. Pediatric oncology evaluation was completely normal. Eighteen months after presentation, the patient remained healthy without recurrence of the lesion. CONCLUSIONS: Rare cases of congenital histiocytosis can present as a solitary lesion over the palpebral conjunctiva, without skin or systemic involvement.

Original language	English
Pages (from-to)	728-730
Number of pages	3
Journal	American Journal of Ophthalmology
Volume	139
Issue number	4
DOIs	https://doi.org/10.1016/j.ajo.2004.10.001
State	Published - 1 Jan 2005

ASJC Scopus subject areas

Ophthalmology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ajo.2004.10.001

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title = "Isolated congenital histiocytosis in the palpebral conjunctiva in a newborn.",

abstract = "PURPOSE: To report a rare case of congenital histiocytosis in a newborn without skin involvement. DESIGN: Interventional case-report. METHODS: A full-term baby presented with a mass over the palpebral conjunctiva of his left upper lid. Ophthalmic examination was otherwise normal, and the baby was healthy. There were no skin lesions. RESULTS: The lesion was completely removed surgically. Pathologic examination demonstrated a cellular infiltrate composed of eosinophils and histiocytes. Immunohistochemistry disclosed positive stain for protein S-100 and CD1 antigenic determinant. Pediatric oncology evaluation was completely normal. Eighteen months after presentation, the patient remained healthy without recurrence of the lesion. CONCLUSIONS: Rare cases of congenital histiocytosis can present as a solitary lesion over the palpebral conjunctiva, without skin or systemic involvement.",

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T1 - Isolated congenital histiocytosis in the palpebral conjunctiva in a newborn.

AU - Monos, Tova

AU - Levy, Jaime

AU - Lifshitz, Tova

AU - Yagev, Ronit

AU - Maor, Esther

PY - 2005/1/1

Y1 - 2005/1/1

N2 - PURPOSE: To report a rare case of congenital histiocytosis in a newborn without skin involvement. DESIGN: Interventional case-report. METHODS: A full-term baby presented with a mass over the palpebral conjunctiva of his left upper lid. Ophthalmic examination was otherwise normal, and the baby was healthy. There were no skin lesions. RESULTS: The lesion was completely removed surgically. Pathologic examination demonstrated a cellular infiltrate composed of eosinophils and histiocytes. Immunohistochemistry disclosed positive stain for protein S-100 and CD1 antigenic determinant. Pediatric oncology evaluation was completely normal. Eighteen months after presentation, the patient remained healthy without recurrence of the lesion. CONCLUSIONS: Rare cases of congenital histiocytosis can present as a solitary lesion over the palpebral conjunctiva, without skin or systemic involvement.

AB - PURPOSE: To report a rare case of congenital histiocytosis in a newborn without skin involvement. DESIGN: Interventional case-report. METHODS: A full-term baby presented with a mass over the palpebral conjunctiva of his left upper lid. Ophthalmic examination was otherwise normal, and the baby was healthy. There were no skin lesions. RESULTS: The lesion was completely removed surgically. Pathologic examination demonstrated a cellular infiltrate composed of eosinophils and histiocytes. Immunohistochemistry disclosed positive stain for protein S-100 and CD1 antigenic determinant. Pediatric oncology evaluation was completely normal. Eighteen months after presentation, the patient remained healthy without recurrence of the lesion. CONCLUSIONS: Rare cases of congenital histiocytosis can present as a solitary lesion over the palpebral conjunctiva, without skin or systemic involvement.

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Isolated congenital histiocytosis in the palpebral conjunctiva in a newborn.

Abstract

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