Laboratory evaluation of different agar media for isolation of carbapenem-resistant Acinetobacter spp

J. Moran-Gilad, A. Adler, D. Schwartz, S. Navon-Venezia, Y. Carmeli

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The optimal method for surveillance of carbapenem-resistant Acinetobacter spp. (CRAB) is unknown. A collection of CRAB strains (n = 42), carbapenem-susceptible strains (CSAB), and non-Acinetobacter strains (n = 18) was used to evaluate six laboratory surveillance methods: MacConkey (MAC), MAC + 1 μg/ml imipenem (MAC-IPM), minimal salts agar + 1 % acetate (MSA), MSA with IPM disk (MSA-IPM), CHROMagarKPC, and CHROMagar Acinetobacter with CR102 (CHROMAcineto). CHROMAcineto was 100 % sensitive and specific. CHROMagarKPC and MAC-IPM were highly sensitive (>95 %), but their specificity was substantially hampered by the breakthrough growth of CSAB. MSA was unsuitable for CRAB detection. CHROMAcineto is a promising medium for CRAB detection and warrants further clinical evaluation.

Original languageEnglish
Pages (from-to)1909-1913
Number of pages5
JournalEuropean Journal of Clinical Microbiology and Infectious Diseases
Volume33
Issue number11
DOIs
StatePublished - 19 Oct 2014
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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