Abstract
Changes in serum creatine phosphokinase have been associated with exacerbation of tardive dyskinesia. Vitamin E, a drug suggested to be effective in the treatment of tardive dyskinesia, has been implicated as a possible cause of increased creatine phosphokinase levels. Ten patients with long-term tardive dyskinesia were treated with vitamin E in a double-blind, placebo-controlled crossover study. Vitamin E blood levels and creatine phosphokinase serum levels were monitored at various phases during the study. There were no significant differences between vitamin E and placebo treated patients in their abilities to affect tardive dyskinesia or to influence creatine phosphokinase levels. These data do not support the hypothesis that administration of vitamin E may alter creatine phosphokinase levels in patients with long-term tardive dyskinesia.
Original language | English |
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Pages (from-to) | 171-173 |
Number of pages | 3 |
Journal | International Clinical Psychopharmacology |
Volume | 12 |
Issue number | 3 |
DOIs | |
State | Published - 1 Jan 1997 |
Externally published | Yes |
Keywords
- Creatine phosphokinase
- Tardive dyskinesia
- Vitamin E
ASJC Scopus subject areas
- Psychiatry and Mental health
- Pharmacology (medical)