Laparoscopically assisted uterine fibroid cryoablation

Moty Pansky, Bryan D. Cowan, Maya Frank, Harriette L. Hampton, Stephen Zimberg

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Objective: The objective of the study was to develop a safe and effective cryoablation technique for the treatment of uterine fibroids. Study Design: This was a multicenter pilot case series to evaluate cryoablation of uterine fibroids using laparoscopically assisted placement of 17-gauge cryoablation needles. Patient satisfaction was documented with a validated Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire. Procedural efficacy was evaluated by assessing fibroid shrinkage. Treatment was followed by assessments at 3, 6, and 12 months. Results: Median fibroid volume reduction was 43.3% (19 patients) and 66.4% (15 patients) at 6 and 12 months, respectively. Median UFS-QOL score improvement was 61.9% and 66.7% at 6 and 12 months, respectively. Additionally, patients experienced marked improvement of bleeding and fibroid bulk symptoms. The median Symptom Severity Score at baseline was 50, 25.0 (-59%) at 6 months, and 12.5 (-66.7%) at 12 months. Conclusion: These pilot data indicate that uterine fibroid cryoablation is a safe and effective minimally invasive alternative to treat symptomatic uterine fibroids.

Original languageEnglish
Pages (from-to)571.e1-571.e7
JournalAmerican Journal of Obstetrics and Gynecology
Issue number6
StatePublished - 1 Jan 2009
Externally publishedYes


  • cryo
  • cryoablation
  • cryotherapy
  • fibroid
  • leiomyoma
  • quality of life

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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