Larvicidal activity of saponin containing extracts and fractions of fruit mesocarp of Balanites aegyptiaca

Zeev Wiesman; Bishnu P. Chapagain

doi:10.1016/j.fitote.2006.05.012

Larvicidal activity of saponin containing extracts and fractions of fruit mesocarp of Balanites aegyptiaca

Zeev Wiesman, Bishnu P. Chapagain

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70 Scopus citations

Abstract

Chloroform, ethyl acetate, butanol and methanol extracts of fruit mesocarp of Balanites aegyptiaca and five fractions from the methanol extract were tested against the Aedes aegypti mosquito larvae. All extracts showed larvicidal effects however the highest larval mortality was found in methanol extract. One fraction obtained from the silica gel column chromatography of the latter was found most effective for larval mortality. This fraction also interfered with adult emergence. A concentration of 0.0014% (w/v) of this active fraction showed inhibition of the 50% of the test larval population from emerging adults (EC₅₀). The analysis of total saponin content of these tested extracts and fractions revealed a strong correlation between saponin content and larval mortality.

Original language	English
Pages (from-to)	420-424
Number of pages	5
Journal	Fitoterapia
Volume	77
Issue number	6
DOIs	https://doi.org/10.1016/j.fitote.2006.05.012
State	Published - 1 Jan 2006

Keywords

Aedes aegypti
Balanites aegyptiaca
Larvicidal activity
Saponins

ASJC Scopus subject areas

Pharmacology
Drug Discovery

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10.1016/j.fitote.2006.05.012

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title = "Larvicidal activity of saponin containing extracts and fractions of fruit mesocarp of Balanites aegyptiaca",

abstract = "Chloroform, ethyl acetate, butanol and methanol extracts of fruit mesocarp of Balanites aegyptiaca and five fractions from the methanol extract were tested against the Aedes aegypti mosquito larvae. All extracts showed larvicidal effects however the highest larval mortality was found in methanol extract. One fraction obtained from the silica gel column chromatography of the latter was found most effective for larval mortality. This fraction also interfered with adult emergence. A concentration of 0.0014% (w/v) of this active fraction showed inhibition of the 50% of the test larval population from emerging adults (EC50). The analysis of total saponin content of these tested extracts and fractions revealed a strong correlation between saponin content and larval mortality.",

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T1 - Larvicidal activity of saponin containing extracts and fractions of fruit mesocarp of Balanites aegyptiaca

AU - Wiesman, Zeev

AU - Chapagain, Bishnu P.

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N2 - Chloroform, ethyl acetate, butanol and methanol extracts of fruit mesocarp of Balanites aegyptiaca and five fractions from the methanol extract were tested against the Aedes aegypti mosquito larvae. All extracts showed larvicidal effects however the highest larval mortality was found in methanol extract. One fraction obtained from the silica gel column chromatography of the latter was found most effective for larval mortality. This fraction also interfered with adult emergence. A concentration of 0.0014% (w/v) of this active fraction showed inhibition of the 50% of the test larval population from emerging adults (EC50). The analysis of total saponin content of these tested extracts and fractions revealed a strong correlation between saponin content and larval mortality.

AB - Chloroform, ethyl acetate, butanol and methanol extracts of fruit mesocarp of Balanites aegyptiaca and five fractions from the methanol extract were tested against the Aedes aegypti mosquito larvae. All extracts showed larvicidal effects however the highest larval mortality was found in methanol extract. One fraction obtained from the silica gel column chromatography of the latter was found most effective for larval mortality. This fraction also interfered with adult emergence. A concentration of 0.0014% (w/v) of this active fraction showed inhibition of the 50% of the test larval population from emerging adults (EC50). The analysis of total saponin content of these tested extracts and fractions revealed a strong correlation between saponin content and larval mortality.

KW - Aedes aegypti

KW - Balanites aegyptiaca

KW - Larvicidal activity

KW - Saponins

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Larvicidal activity of saponin containing extracts and fractions of fruit mesocarp of Balanites aegyptiaca

Abstract

Keywords

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