TY - JOUR
T1 - Laser-assisted corticoid delivery for the treatment of burn scars
AU - Menashe, Shaked
AU - Heller, Lior
AU - Ofek, Andre
AU - Moscovici, Sharon
AU - Dor, Omer
AU - Sorkin, Alex
AU - Govrin-Yehudain, Yoad
AU - Hadad, Eran
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025.
PY - 2025/12/1
Y1 - 2025/12/1
N2 - Background: Non-fatal burns impact millions annually, are difficult to treat, and reduce quality of life. Laser technology offers a promising approach for improving scar outcomes, in particular, laser-assisted drug delivery (LADD), which has shown effective results in various dermatological conditions. The aim of this study is to evaluate advanced laser technology in combination with steroid administration for the treatment of abnormal burn scars. Methods: This retrospective single-center study evaluated burn scars treated with laser-assisted corticoid trans-epidermal delivery. Scar severity was assessed using the Vancouver Scar Scale (VSS), and patient ratings were obtained from the Patient and Observer Scar Assessment Scale (POSAS). Statistical analyses compared six-month follow-up scores to baseline and examined group differences and associations between key variables and treatment efficacy. Results: A total of 32 scars were evaluated. Following treatment, significant improvements (p < 0.05) were observed in all scar characteristics, as indicated by both physician assessments and patient ratings. A strong positive correlation was found between physician and patient-rated outcomes (Spearman’s correlation: 0.67). The impact of group-level factors yielded mixed results. There were no major side effects, with only transient hyperpigmentation observed after treatment. Conclusions: The combined laser and corticoid treatment of burn scars has proved to be safe, effective, and versatile. Level of evidence: Level V, therapeutic study.
AB - Background: Non-fatal burns impact millions annually, are difficult to treat, and reduce quality of life. Laser technology offers a promising approach for improving scar outcomes, in particular, laser-assisted drug delivery (LADD), which has shown effective results in various dermatological conditions. The aim of this study is to evaluate advanced laser technology in combination with steroid administration for the treatment of abnormal burn scars. Methods: This retrospective single-center study evaluated burn scars treated with laser-assisted corticoid trans-epidermal delivery. Scar severity was assessed using the Vancouver Scar Scale (VSS), and patient ratings were obtained from the Patient and Observer Scar Assessment Scale (POSAS). Statistical analyses compared six-month follow-up scores to baseline and examined group differences and associations between key variables and treatment efficacy. Results: A total of 32 scars were evaluated. Following treatment, significant improvements (p < 0.05) were observed in all scar characteristics, as indicated by both physician assessments and patient ratings. A strong positive correlation was found between physician and patient-rated outcomes (Spearman’s correlation: 0.67). The impact of group-level factors yielded mixed results. There were no major side effects, with only transient hyperpigmentation observed after treatment. Conclusions: The combined laser and corticoid treatment of burn scars has proved to be safe, effective, and versatile. Level of evidence: Level V, therapeutic study.
UR - http://www.scopus.com/inward/record.url?scp=85217502754&partnerID=8YFLogxK
U2 - 10.1007/s00238-025-02270-0
DO - 10.1007/s00238-025-02270-0
M3 - Article
AN - SCOPUS:85217502754
SN - 0930-343X
VL - 48
JO - European Journal of Plastic Surgery
JF - European Journal of Plastic Surgery
IS - 1
M1 - 10
ER -