LC-PUFA from photosynthetic microalgae: Occurrence, biosynthesis, and prospects in biotechnology

Inna Khozin-Goldberg, Umidjon Iskandarov, Zvi Cohen

Research output: Contribution to journalReview articlepeer-review

162 Scopus citations


Microalgae offer potential for numerous commercial applications, among them the production of long-chain polyunsaturated fatty acids (LC-PUFAs). These valuable fatty acids are important for a variety of nutraceutical and pharmaceutical purposes, and the market for these products is continually growing. An appropriate ratio of LC-PUFA of the ω-3 and ω-6 groups is vital for "healthy" nutrition, and adequate dietary intake has strong health benefits in humans. Microalgae of diverse classes are primary natural producers of LC-PUFA. This mini-review presents an introductory overview of LC-PUFA-related health benefits in humans, describes LC-PUFA occurrence in diverse microalgal classes, depicts the major pathways of their biosynthesis in microalgae, and discusses the prospects for microalgal LC-PUFA production.

Original languageEnglish
Pages (from-to)905-915
Number of pages11
JournalApplied Microbiology and Biotechnology
Issue number4
StatePublished - 1 Aug 2011


  • Arachidonic acid
  • Desaturase
  • Docosahexaenoic acid
  • Eicosapentaenoic acid
  • Microalgae

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology


Dive into the research topics of 'LC-PUFA from photosynthetic microalgae: Occurrence, biosynthesis, and prospects in biotechnology'. Together they form a unique fingerprint.

Cite this