Leave-one-trial-out, LOTO, a general approach to link single-trial parameters of cognitive models to neural data

Sebastian Gluth, Nachshon Meiran

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

A key goal of model-based cognitive neuroscience is to estimate the trial-by-trial fluctuations of cognitive model parameters in order to link these fluctuations to brain signals. However, previously developed methods are limited by being difficult to implement, time-consuming, or model-specific. Here, we propose an easy, efficient and general approach to estimating trial-wise changes in parameters: Leave-One-Trial-Out (LOTO). The rationale behind LOTO is that the difference between parameter estimates for the complete dataset and for the dataset with one omitted trial reflects the parameter value in the omitted trial. We show that LOTO is superior to estimating parameter values from single trials and compare it to previously proposed approaches. Furthermore, the method makes it possible to distinguish true variability in a parameter from noise and from other sources of variability. In our view, the practicability and generality of LOTO will advance research on tracking fluctuations in latent cognitive variables and linking them to neural data.

Original languageEnglish
Article numbere42607
JournaleLife
Volume8
DOIs
StatePublished - 1 Feb 2019

Fingerprint

Dive into the research topics of 'Leave-one-trial-out, LOTO, a general approach to link single-trial parameters of cognitive models to neural data'. Together they form a unique fingerprint.

Cite this