Lesion-symptom mapping

Dagmar Timmann, Thomas M. Ernst, Winfried Ilg, Opher Donchin

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

A traditional approach to studying cerebellar function is examining impairment in human subjects with cerebellar disease. High-resolution structural brain imaging coupled with tools that perform lesion-symptom mapping produced major advances in localization of function within the human cerebellum. Lesionsymptom mapping is also called lesion-behavior mapping and lesion-defi cit mapping. To localize function, patients should be included who have lesions restricted to the cerebellum. These patients are rare. Group sizes are commonly much smaller than in comparable studies with cerebral stroke. Methods will be discussed which are currently available to perform lesion-symptom mapping in patients with focal and degenerative cerebellar disease.

Original languageEnglish
Title of host publicationEssentials of Cerebellum and Cerebellar Disorders
Subtitle of host publicationA Primer for Graduate Students
PublisherSpringer International Publishing
Pages489-497
Number of pages9
ISBN (Electronic)9783319245515
ISBN (Print)9783319245492
DOIs
StatePublished - 1 Jan 2016

Keywords

  • Cerebellar function
  • Lesion-behavior
  • Lesion-defi cit
  • Lesion-symptom
  • Mapping

ASJC Scopus subject areas

  • Medicine (all)
  • Biochemistry, Genetics and Molecular Biology (all)
  • Neuroscience (all)
  • Agricultural and Biological Sciences (all)

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