Abstract
A Lewis-acid-mediated domino reaction of 2/3-(bromomethyl)indoles with arenes/heteroarenes led to the formation of the corresponding annulated carbazoles. This three-step one-pot transformation proceeds by sequential Lewis acid catalysed Friedel-Crafts alkylation, electrocyclization and aromatization reactions. The strategy is highly efficient for the assembly of complex aryl/heteroaryl-fused carbazoles.
Original language | English |
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Pages (from-to) | 922-935 |
Number of pages | 14 |
Journal | European Journal of Organic Chemistry |
Issue number | 5 |
DOIs | |
State | Published - 1 Feb 2011 |
Externally published | Yes |
Keywords
- Annulation
- Domino reactions
- Electrocyclization
- Friedel-Crafts reactions
- Fused ring systems
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry